Oscillatory Oxido-Reductive Reaction of Intracellular Hemoglobin in Human Erythrocyte Incubated with ο-Aminophenol

P-2: Study The Effect of Oral Zinc Supplementation on Thiol Oxido-Reductive Index in Spermatozoa of Patients with Asthenospermia

Background: There are several causes leading to male infertility, like oxidative stress, and nutritional deficiency of trace elements i.e., selenium and zinc. The Zinc is the following only to iron as the most abundant element in the body. Although, Zinc is found in red meat, white meat, fish, and milk; the World Health Organization (WHO) approximates that one-third of world population is defic...

Metabolism of pyrogallol to purpurogallin by human erythrocytic hemoglobin.

The aim of this study was to investigate the oxido-reductive reactions of human hemoglobin with pyrogallol and the metabolism of pyrogallol by the protein, which contains a protoporphyrin IX like cytochrome P-450. Pyrogallol, having three hydroxy groups at the adjacent positions in the benzene ring, oxidized human oxyhemoglobin to methemoglobin and reduced human methemoglobin to oxyhemoglobin. ...

Reaction of CO2 with human hemoglobin solution.

Human αB-Crystallin Mutation Causes Oxido-Reductive Stress and Protein Aggregation Cardiomyopathy in Mice

The autosomal dominant mutation in the human alphaB-crystallin gene inducing a R120G amino acid exchange causes a multisystem, protein aggregation disease including cardiomyopathy. The pathogenesis of cardiomyopathy in this mutant (hR120GCryAB) is poorly understood. Here, we show that transgenic mice overexpressing cardiac-specific hR120GCryAB recapitulate the cardiomyopathy in humans and find ...

The Reaction of n-Butyl Isocyanide with Human Hemoglobin

At pH 7.0, ZOO, both in the absence and presence of phosphates, the time course of n-butyl isocyanide binding to deoxyhemoglobin is biphasic, and the two kinetic phases can be isolated spectrally and identified with the properties of the a and /3 chains. Under all conditions at this pH, both the association and dissociation rate constants of the p chains are at least 10 times larger than the co...